![Immunofluorescence analysis of U-2 OS cells using [KO Validated] MTA2 Rabbit monoclonal antibody (STJ11102119) at dilution of 1 : 100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/91036/361850/STJ11102119_2__16220.1713126765.jpg?c=1 "Immunofluorescence analysis of U-2 OS cells using [KO Validated] MTA2 Rabbit monoclonal antibody (STJ11102119) at dilution of 1 : 100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
![Western blot analysis of lysates from wild type (WT) and MTA2 knockout (KO) 293T cells, using [KO Validated] MTA2 Rabbit monoclonal antibody (STJ11102119) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/91036/361852/STJ11102119_4__66670.1713126767.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MTA2 knockout (KO) 293T cells, using [KO Validated] MTA2 Rabbit monoclonal antibody (STJ11102119) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.")
| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA/ChIP |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S9MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. ChIP:5 Mu g antibody for 10 Mu g-15 Mu g of Chromat |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTA2 |
| Gene ID: | 9219 |
| Uniprot ID: | MTA2_HUMAN |
| Immunogen Region: | 569-668 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 569-668 of human MTA2 (O94776). |
| Immunogen Sequence: | GVPFSANGRPLASGIRSSSQ PAAKRQKLNPADAPNPVVFV ATKDTRALRKALTHLEMRRA ARRPNLPLKVKPTLIAVRPP VPLPAPSHPASTNEPIVLED |
| Tissue Specificity | Widely expressed. |
| Function | May function as a transcriptional coregulator. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. |
| Protein Name | Metastasis-Associated Protein Mta2 Metastasis-Associated 1-Like 1 Mta1-L1 Protein P53 Target Protein In Deacetylase Complex |
| Database Links | Reactome: R-HSA-3214815 Reactome: R-HSA-427389 Reactome: R-HSA-6804758 Reactome: R-HSA-73762 Reactome: R-HSA-8943724 Reactome: R-HSA-9679191 Reactome: R-HSA-9843940 Reactome: R-HSA-9844594 Reactome: R-HSA-9845323 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Metastasis-Associated Protein Mta2 antibody Anti-Metastasis-Associated 1-Like 1 antibody Anti-Mta1-L1 Protein antibody Anti-P53 Target Protein In Deacetylase Complex antibody Anti-MTA2 antibody Anti-MTA1L1 antibody Anti-PID antibody |
Information sourced from Uniprot.org