| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MT-CYB |
| Gene ID: | 4519 |
| Uniprot ID: | CYB_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MT-CYB (YP_003024038.1). |
| Immunogen Sequence: | RGLYYGSFLYSETWNIGIIL LLATMATAFMGYVLPWGQMS FWGATVITNLLSAIPYIGTD LVQWIWGGYSVDSPTLTRFF TFHFILPFIIAALATLHLLF L |
| Function | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. |
| Protein Name | Cytochrome BComplex Iii Subunit 3Complex Iii Subunit IiiCytochrome B-C1 Complex Subunit 3Ubiquinol-Cytochrome-C Reductase Complex Cytochrome B Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-9865881 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cytochrome B antibodyAnti-Complex Iii Subunit 3 antibodyAnti-Complex Iii Subunit Iii antibodyAnti-Cytochrome B-C1 Complex Subunit 3 antibodyAnti-Ubiquinol-Cytochrome-C Reductase Complex Cytochrome B Subunit antibodyAnti-MT-CYB antibodyAnti-COB antibodyAnti-CYTB antibodyAnti-MTCYB antibody |
Information sourced from Uniprot.org