| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MSRA |
| Gene ID: | 4482 |
| Uniprot ID: | MSRA_HUMAN |
| Immunogen Region: | 24-235 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-235 of human MSRA (NP_036463.1). |
| Immunogen Sequence: | GNSASNIVSPQEALPGRKEQ TPVAAKHHVNGNRTVEPFPE GTQMAVFGMGCFWGAERKFW VLKGVYSTQVGFAGGYTSNP TYKEVCSEKTGHAEVVRVVY QPEHMSFEELLKVFWENHDP TQGMRQGNDHGTQYRSAIYP TSAKQMEAALSSKENYQKVL SEHGFGPITTDIREGQTFYY AEDYHQQYLSKNPNGYCGLG GTGVSCPVGIKK |
| Tissue Specificity | Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus. |
| Function | Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. |
| Protein Name | Mitochondrial Peptide Methionine Sulfoxide ReductasePeptide-MethionineS-S-Oxide ReductasePeptide Met(O ReductaseProtein-Methionine-S-Oxide ReductasePmsr |
| Database Links | Reactome: R-HSA-5676934 |
| Cellular Localisation | Isoform 1: MitochondrionIsoform 2: CytoplasmIsoform 3: CytoplasmNucleusIsoform 5: CytoplasmMembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Mitochondrial Peptide Methionine Sulfoxide Reductase antibodyAnti-Peptide-Methionine antibodyAnti-S-S-Oxide Reductase antibodyAnti-Peptide Met(O Reductase antibodyAnti-Protein-Methionine-S-Oxide Reductase antibodyAnti-Pmsr antibodyAnti-MSRA antibody |
Information sourced from Uniprot.org