• Immunohistochemistry analysis of MSR1 in paraffin-embedded mouse testis using MSR1 Rabbit monoclonal antibody (STJ11103491) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of MSR1 in paraffin-embedded rat brain using MSR1 Rabbit monoclonal antibody (STJ11103491) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using MSR1 Rabbit monoclonal antibody (STJ11103491) at 1:1000 dilution. C6 cells were treated by LPS for 6 hours and Brefeldin A for 3 hours of stimulation. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-MSR1 antibody (1-100) [S1MR] (STJ11103491)

SKU:
STJ11103491

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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-MSR1 (1-100) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MSR1
Gene ID: 4481
Uniprot ID: MSRE_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MSR1 (P21757).
Immunogen Sequence: MEQWDHFHNQQEDTDSCSES VKFDARSMTALLPPNPKNSP SLQEKLKSFKAALIALYLLV FAVLIPLIGIVAAQLLKWET KNCSVSSTNANDITQSLTGK
Tissue Specificity Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain.
Function Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
Protein Name Macrophage Scavenger Receptor Types I And Ii
Macrophage Acetylated Ldl Receptor I And Ii
Scavenger Receptor Class A Member 1
Cd Antigen Cd204
Database Links Reactome: R-HSA-3000480
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Macrophage Scavenger Receptor Types I And Ii antibody
Anti-Macrophage Acetylated Ldl Receptor I And Ii antibody
Anti-Scavenger Receptor Class A Member 1 antibody
Anti-Cd Antigen Cd204 antibody
Anti-MSR1 antibody
Anti-SCARA1 antibody

Information sourced from Uniprot.org

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