Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-MSR1 (1-100) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S1MR |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MSR1 |
Gene ID: |
4481 |
Uniprot ID: |
MSRE_HUMAN |
Immunogen Region: |
1-100 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MSR1 (P21757). |
Immunogen Sequence: |
MEQWDHFHNQQEDTDSCSES VKFDARSMTALLPPNPKNSP SLQEKLKSFKAALIALYLLV FAVLIPLIGIVAAQLLKWET KNCSVSSTNANDITQSLTGK |
Tissue Specificity | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain. |
Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
Protein Name | Macrophage Scavenger Receptor Types I And IiMacrophage Acetylated Ldl Receptor I And IiScavenger Receptor Class A Member 1Cd Antigen Cd204 |
Database Links | Reactome: R-HSA-3000480 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Macrophage Scavenger Receptor Types I And Ii antibodyAnti-Macrophage Acetylated Ldl Receptor I And Ii antibodyAnti-Scavenger Receptor Class A Member 1 antibodyAnti-Cd Antigen Cd204 antibodyAnti-MSR1 antibodyAnti-SCARA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance