| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MSH5 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments gave an approx 38kDa band in Human Testis, Tonsil and Thymus lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanation |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MSH5 |
| Gene ID: | 4439 |
| Uniprot ID: | MSH5_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_079535.3 ; NP_751897.1; NP_002432.1 |
| Specificity: | This antibody is expected to recognise three reported isoforms ( NP_079535.3 ; NP_751897.1; NP_002432.1) ; Reported variants NP_751898.1 and NP_002432.1 represent identical protein. |
| Immunogen Sequence: | GDLHCEIRDQET |
| Function | Involved in DNA mismatch repair and meiotic recombination processes. Facilitates crossovers between homologs during meiosis. |
| Protein Name | Muts Protein Homolog 5Hmsh5 |
| Database Links | Reactome: R-HSA-912446 |
| Alternative Antibody Names | Anti-Muts Protein Homolog 5 antibodyAnti-Hmsh5 antibodyAnti-MSH5 antibody |
Information sourced from Uniprot.org