Anti-MRPS27 antibody (255-414) (STJ113268)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MRPS27 (255-414) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRPS27 |
| Gene ID | 23107 |
| Uniprot ID | RT27_HUMAN |
| Immunogen Region | 255-414 |
| Immunogen Sequence | YLDRALQVMEKVAASPEDIK LCREALDVLGAVLKALTSAD GASEEQSQNDEDNQGSEKLV EQLDIEETEQSKLPQYLERF KALHSKLQALGKIESEGLLS LTTQLVKEKLSTCEAEDIAT YEQNLQQWHLDLVQLIQREQ QQREQAKQEYQAQKAAKASA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 255-414 of human MRPS27 (NP_055899.2). |
Additional Info
| Tissue Specificity | Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level). Ubiquitous. |
| Function | RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth. |
| Protein Name | Small Ribosomal Subunit Protein Ms2728s Ribosomal Protein S27 - MitochondrialMrp-S27S27mtMitochondrial Ribosomal Protein S27 |
| Database Links | Reactome: R-HSA-5368286Reactome: R-HSA-5389840Reactome: R-HSA-5419276 |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Small Ribosomal Subunit Protein Ms27 antibodyAnti-28s Ribosomal Protein S27 - Mitochondrial antibodyAnti-Mrp-S27 antibodyAnti-S27mt antibodyAnti-Mitochondrial Ribosomal Protein S27 antibodyAnti-MRPS27 antibodyAnti-KIAA0264 antibody |
Information sourced from Uniprot.org