Anti-MRPL18 antibody (42-180) (STJ11100146)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Mrpl18 (42-180) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Mrpl18 |
| Gene ID | 67681 |
| Uniprot ID | RM18_MOUSE |
| Immunogen Region | 42-180 |
| Immunogen Sequence | EAVAPEFTNRNPRNLELLGV ARKERGWATVWPNREFWHRL RVVKTQHHVEAFVEHLNGQV VVSASTREWAIKKHLYSTRN VVACESIGRVLAQRCLEAGI NFMVYQPTPWEASSDSIKRL QNAMTESGVMLREPRRIYE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 42-180 of mouse Mrpl18 (NP_080586.1). |
Additional Info
| Function | Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity.is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. |
| Protein Name | Large Ribosomal Subunit Protein Ul18m39s Ribosomal Protein L18 - MitochondrialL18mtMrp-L18 |
| Database Links | Reactome: R-MMU-5389840Reactome: -MMU-5419276 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Ul18m antibodyAnti-39s Ribosomal Protein L18 - Mitochondrial antibodyAnti-L18mt antibodyAnti-Mrp-L18 antibodyAnti-Mrpl18 antibody |
Information sourced from Uniprot.org