Immunohistochemistry of rat spleen with Anti-MRP1 primary antibody (STJ501801) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-MRP1 antibody (STJ501801)

SKU:
STJ501801-100
£427.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-MRP1 is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:20, 000
IP: 1:200
IHC: 1:100
ICC: 1:100
IF: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Abcc1
Gene ID: 24565
Uniprot ID: MRP1_RAT
Immunogen: Synthetic peptide corresponding to unique amino acid sequences on rat multidrug resistance-associated protein 1.
Tissue Specificity Skeletal muscle, brain, heart, spleen, lung and kidney.
Post Translational Modifications Glycosylated.
Function Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation. Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells.
Protein Name Multidrug Resistance-Associated Protein 1
Atp-Binding Cassette Sub-Family C Member 1
Glutathione-S-Conjugate-Translocating Atpase Abcc1
Leukotriene C(4 Transporter
Ltc4 Transporter
Database Links Reactome: R-RNO-1660661
Reactome: -RNO-189483
Reactome: -RNO-2142691
Reactome: -RNO-382556
Reactome: -RNO-9707564
Reactome: -RNO-9753281
Reactome: -RNO-9758890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Multidrug Resistance-Associated Protein 1 antibody
Anti-Atp-Binding Cassette Sub-Family C Member 1 antibody
Anti-Glutathione-S-Conjugate-Translocating Atpase Abcc1 antibody
Anti-Leukotriene C(4 Transporter antibody
Anti-Ltc4 Transporter antibody
Anti-Abcc1 antibody
Anti-Mrp1 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ504460 MRP1 Positive Control for STJ501801 peptide (STJ504460) WB
STJ504385 MRP1 Blocking Peptide for STJ501801 peptide (STJ504385) Immunodepletion/Immunocompetition
STJ16100887 Anti-MRP1 antibody [MRPm6] (STJ16100887) Mouse Monoclonal Human FC/WB/ICC/IHC-F/IHC-P
STJ16100889 Anti-MRP1 antibody [MRPm5] (STJ16100889) Mouse Monoclonal Human IHC-F/IHC-P/ICC/FC/WB
STJ16100888 Anti-MRP1 antibody [MRPr1] (STJ16100888) Rat Monoclonal Human FC/WB/ICC/IHC-F/IHC-P
STJ501802 Anti-MRP1 antibody {Biotin} (STJ501802) Rabbit Polyclonal Mouse/Rat ELISA/IHC/IP/WB
STJ501803 Anti-MRP1 antibody {FITC} (STJ501803) Rabbit Polyclonal Mouse/Rat ELISA/IHC/IP/WB
STJ11103479 Anti-MRP1/ABCC1 antibody (210-304) [S9MR] (STJ11103479) Rabbit Monoclonal Human/Mouse/Rat WB/IHC-P/ELISA
STJ16101078 Anti-MRP14/S100A9/calgranulin B antibody [47-8D3] (STJ16101078) Mouse Monoclonal Baboon/Cat/Cow/Dog/Goat/Guinea Pig/Human/Horse/Monkey/Pig/Rabbit/Rat FC/WB/IF/IHC
!