• Western blot analysis of lysates from MCF-7 cells, using MRGX1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HepG2 cells, using MRGX1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-MRGPRX1 antibody (271-320) (STJ94200)

SKU:
STJ94200

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mas-related G-protein coupled receptor member X1 (271-320) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-p 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MRGPRX1
Gene ID: 259249
Uniprot ID: MRGX1_HUMAN
Immunogen Region: 271-320
Specificity: MRGX1 Polyclonal Antibody detects endogenous levels of MRGX1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320
Tissue Specificity Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
Function Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.
Protein Name Mas-Related G-Protein Coupled Receptor Member X1
Sensory Neuron-Specific G-Protein Coupled Receptor 3/4
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Mas-Related G-Protein Coupled Receptor Member X1 antibody
Anti-Sensory Neuron-Specific G-Protein Coupled Receptor 3/4 antibody
Anti-MRGPRX1 antibody
Anti-MRGX1 antibody
Anti-SNSR3 antibody
Anti-SNSR4 antibody

Information sourced from Uniprot.org

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