| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Multiple PDZ domain protein (1564-1614 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:50-300 ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MPDZ |
| Gene ID: | 8777 |
| Uniprot ID: | MPDZ_HUMAN |
| Immunogen Region: | 1564-1614 aa |
| Specificity: | This antibody detects endogenous levels of MPDZ at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human MPDZ at the amino acid range 1564-1614 |
| Function | Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. Promotes clustering of HT2RC at the cell surface. |
| Protein Name | Multiple Pdz Domain Protein Multi-Pdz Domain Protein 1 |
| Cellular Localisation | Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Apical Cell Membrane Postsynaptic Density Cell Projection Dendrite Cell Junction Tight Junction Synapse Synaptosome Colocalizes With Htr2c On The Apical Membrane Of Epithelial Choroid Plexus Cells Highly Enriched In Postsynaptic Densities (Psd) Localized To Punctae On Dendrites Of Hippocampal Neurons And Colocalizes With The Synaptic Marker Dlg4 Localized Mainly In The Schmidt-Lanterman Incisures Of Myelinating Schwann Cells In The Retina Localizes To The Sub-Apical Region Adjacent To The Adherens Junction Complex At The Outer Limiting Membrane Enriched At The Tight Junctions Of Epithelial Cells Association To The Tight Junctions Depends On Cxadr |
| Alternative Antibody Names | Anti-Multiple Pdz Domain Protein antibody Anti-Multi-Pdz Domain Protein 1 antibody Anti-MPDZ antibody Anti-MUPP1 antibody |
Information sourced from Uniprot.org