• Western blot analysis of the lysates from COLO205 cells using MORF4L1 antibody.
  • Western blot analysis of lysates from mouse kidney cells, using MORF4L1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HepG2 cells, using MORF4L1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Western blot analysis of Mouse-kidney mouse-brain lysis using MRG15 antibody. Antibody was diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).
  • Western blot analysis of mouse cells using MRG15 Polyclonal Antibody diluted at 1：500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-MORF4L1 antibody (31-80) (STJ94196)

SKU:
STJ94196

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mortality factor 4-like protein 1 (31-80) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MORF4L1
Gene ID: 10933
Uniprot ID: MO4L1_HUMAN
Immunogen Region: 31-80
Specificity: MRG15 Polyclonal Antibody detects endogenous levels of MRG15 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MORF4L1. AA range:31-80
Function Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.
Protein Name Mortality Factor 4-Like Protein 1
Morf-Related Gene 15 Protein
Protein Msl3-1
Transcription Factor-Like Protein Mrg15
Database Links Reactome: R-HSA-3214847
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Mortality Factor 4-Like Protein 1 antibody
Anti-Morf-Related Gene 15 Protein antibody
Anti-Protein Msl3-1 antibody
Anti-Transcription Factor-Like Protein Mrg15 antibody
Anti-MORF4L1 antibody
Anti-MRG15 antibody
Anti-FWP006 antibody
Anti-HSPC008 antibody
Anti-HSPC061 antibody
Anti-PP368 antibody

Information sourced from Uniprot.org

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