Host: |
Rabbit |
Applications: |
WB/IHC-P/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MOK |
Gene ID: |
5891 |
Uniprot ID: |
MOK_HUMAN |
Immunogen Region: |
1-230 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MOK (NP_055041.1). |
Immunogen Sequence: |
MKNYKAIGKIGEGTFSEVMK MQSLRDGNYYACKQMKQRFE SIEQVNNLREIQALRRLNPH PNILMLHEVVFDRKSGSLAL ICELMDMNIYELIRGRRYPL SEKKIMHYMYQLCKSLDHIH RNGIFHRDVKPENILIKQDV LKLGDFGSCRSVYSKQPYTE YISTRWYRAPECLLTDGFYT YKMDLWSAGCVFYEIASLQP LFPGVNELDQISKIHDVIGT PAQKILTKFK |
Tissue Specificity | Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina. |
Post Translational Modifications | Autophosphorylated. |
Function | Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner. |
Protein Name | Mapk/Mak/Mrk Overlapping KinaseMok Protein KinaseRenal Tumor Antigen 1Rage-1 |
Cellular Localisation | CytoplasmCell ProjectionCiliumNucleus |
Alternative Antibody Names | Anti-Mapk/Mak/Mrk Overlapping Kinase antibodyAnti-Mok Protein Kinase antibodyAnti-Renal Tumor Antigen 1 antibodyAnti-Rage-1 antibodyAnti-MOK antibodyAnti-RAGE antibodyAnti-RAGE1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance