Host: | Rabbit |
Applications: | WB/IF/ICC/ELISA |
Reactivity: | Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Monoclonal |
Clone ID : | S1MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:1000-1:6000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MOG |
Gene ID: | 4340 |
Uniprot ID: | MOG_HUMAN |
Immunogen Region: | 1-100 |
Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Myelin oligodendrocyte glycoprotein (NP_996532.2). |
Immunogen Sequence: | MASLSRPSLPSCLCSFLLLL LLQVSSSYAGQFRVIGPRHP IRALVGDEVELPCRISPGKN ATGMEVGWYRPPFSRVVHLY RNGKDQDGDQAPEYRGRTEL |
Tissue Specificity | Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes. |
Function | Mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. (Microbial infection) Acts as a receptor for rubella virus. |
Protein Name | Myelin-Oligodendrocyte Glycoprotein |
Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 5: Cell MembraneIsoform 2: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell MembraneIsoform 4: Cell MembraneIsoform 6: Cell MembraneIsoform 7: Cell MembraneIsoform 8: Cell MembraneIsoform 9: Cell Membrane |
Alternative Antibody Names | Anti-Myelin-Oligodendrocyte Glycoprotein antibodyAnti-MOG antibody |
Information sourced from Uniprot.org