| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S1MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:6000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MOG |
| Gene ID: | 4340 |
| Uniprot ID: | MOG_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Myelin oligodendrocyte glycoprotein (NP_996532.2). |
| Immunogen Sequence: | MASLSRPSLPSCLCSFLLLL LLQVSSSYAGQFRVIGPRHP IRALVGDEVELPCRISPGKN ATGMEVGWYRPPFSRVVHLY RNGKDQDGDQAPEYRGRTEL |
| Tissue Specificity | Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes. |
| Function | Mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. (Microbial infection) Acts as a receptor for rubella virus. |
| Protein Name | Myelin-Oligodendrocyte Glycoprotein |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 5: Cell MembraneIsoform 2: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell MembraneIsoform 4: Cell MembraneIsoform 6: Cell MembraneIsoform 7: Cell MembraneIsoform 8: Cell MembraneIsoform 9: Cell Membrane |
| Alternative Antibody Names | Anti-Myelin-Oligodendrocyte Glycoprotein antibodyAnti-MOG antibody |
Information sourced from Uniprot.org
![Immunoprecipitation analysis of 300 Mu g extracts from Jurkat cells using 3 Mu g [KD Validated] DNMT1 Rabbit monoclonal antibody (STJ11101761). Western blot was performed from the immunoprecipitate using DNMT1 (STJ11101761) at a dilution of 1:1000.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/90676/360693/STJ11101761_1__79926.1713125393.jpg?c=1 "Immunoprecipitation analysis of 300 Mu g extracts from Jurkat cells using 3 Mu g [KD Validated] DNMT1 Rabbit monoclonal antibody (STJ11101761). Western blot was performed from the immunoprecipitate using DNMT1 (STJ11101761) at a dilution of 1:1000.")
