Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Molybdopterin synthase sulfur carrier subunit is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MOCS2 |
Gene ID: | 4338 |
Uniprot ID: | MOC2A_HUMAN |
Specificity: | This antibody detects endogenous levels of MOCS2B at Human |
Immunogen: | Synthesized peptide derived from human MOCS2B |
Post Translational Modifications | C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3. |
Function | Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. |
Protein Name | Molybdopterin Synthase Sulfur Carrier Subunit Moco1-A Molybdenum Cofactor Synthesis Protein 2 Small Subunit Molybdenum Cofactor Synthesis Protein 2a Mocs2a Molybdopterin-Synthase Small Subunit Sulfur Carrier Protein Mocs2a |
Database Links | Reactome: R-HSA-947581 |
Cellular Localisation | Cytoplasm Cytosol |
Alternative Antibody Names | Anti-Molybdopterin Synthase Sulfur Carrier Subunit antibody Anti-Moco1-A antibody Anti-Molybdenum Cofactor Synthesis Protein 2 Small Subunit antibody Anti-Molybdenum Cofactor Synthesis Protein 2a antibody Anti-Mocs2a antibody Anti-Molybdopterin-Synthase Small Subunit antibody Anti-Sulfur Carrier Protein Mocs2a antibody Anti-MOCS2 antibody Anti-MOCO1 antibody |
Information sourced from Uniprot.org