| Post Translational Modifications | C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3. |
| Function | Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. |
| Protein Name | Molybdopterin Synthase Sulfur Carrier SubunitMoco1-AMolybdenum Cofactor Synthesis Protein 2 Small SubunitMolybdenum Cofactor Synthesis Protein 2aMocs2aMolybdopterin-Synthase Small SubunitSulfur Carrier Protein Mocs2a |
| Database Links | Reactome: R-HSA-947581 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Molybdopterin Synthase Sulfur Carrier Subunit antibodyAnti-Moco1-A antibodyAnti-Molybdenum Cofactor Synthesis Protein 2 Small Subunit antibodyAnti-Molybdenum Cofactor Synthesis Protein 2a antibodyAnti-Mocs2a antibodyAnti-Molybdopterin-Synthase Small Subunit antibodyAnti-Sulfur Carrier Protein Mocs2a antibodyAnti-MOCS2 antibodyAnti-MOCO1 antibody |
Information sourced from Uniprot.org
