| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Molybdopterin synthase sulfur carrier subunit is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MOCS2 |
| Gene ID: |
4338 |
| Uniprot ID: |
MOC2A_HUMAN |
| Specificity: |
This antibody detects endogenous levels of MOCS2B at Human |
| Immunogen: |
Synthesized peptide derived from human MOCS2B |
| Post Translational Modifications | C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3. |
| Function | Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. |
| Protein Name | Molybdopterin Synthase Sulfur Carrier SubunitMoco1-AMolybdenum Cofactor Synthesis Protein 2 Small SubunitMolybdenum Cofactor Synthesis Protein 2aMocs2aMolybdopterin-Synthase Small SubunitSulfur Carrier Protein Mocs2a |
| Database Links | Reactome: R-HSA-947581 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Molybdopterin Synthase Sulfur Carrier Subunit antibodyAnti-Moco1-A antibodyAnti-Molybdenum Cofactor Synthesis Protein 2 Small Subunit antibodyAnti-Molybdenum Cofactor Synthesis Protein 2a antibodyAnti-Mocs2a antibodyAnti-Molybdopterin-Synthase Small Subunit antibodyAnti-Sulfur Carrier Protein Mocs2a antibodyAnti-MOCS2 antibodyAnti-MOCO1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
