• Western blot analysis of the lysates from 293 cells using MNDA antibody.
  • Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Western blot analysis of lysates from LOVO cells, using MNDA Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of 3T3 cells using MNDA Polyclonal Antibody diluted at 1:500

Anti-MNDA antibody (358-407) (STJ94168)

SKU:
STJ94168

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Myeloid cell nuclear differentiation antigen (358-407) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MNDA
Gene ID: 4332
Uniprot ID: MNDA_HUMAN
Immunogen Region: 358-407
Specificity: MNDA Polyclonal Antibody detects endogenous levels of MNDA protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MNDA. AA range:358-407
Tissue Specificity Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appears in myeloblast cells in some cases of acute myeloid Leukemia.
Function May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
Protein Name Myeloid Cell Nuclear Differentiation Antigen
Database Links Reactome: R-HSA-6798695
Cellular Localisation Nucleus
Cytoplasm
Uniformly Distributed Throughout The Interphase Cell Nucleus
Associates With Chromatin
Alternative Antibody Names Anti-Myeloid Cell Nuclear Differentiation Antigen antibody
Anti-MNDA antibody

Information sourced from Uniprot.org

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