| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MMP25 |
| Gene ID: | 64386 |
| Uniprot ID: | MMP25_HUMAN |
| Immunogen Region: | 350-540 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-540 of human MMP25 (NP_071913.1). |
| Immunogen Sequence: | SPRPARLHRFWEGLPAQVRV VQAAYARHRDGRILLFSGPQ FWVFQDRQLEGGARPLTELG LPPGEEVDAVFSWPQNGKTY LVRGRQYWRYDEAAARPDPG YPRDLSLWEGAPPSPDDVTV SNAGDTYFFKGAHYWRFPKN SIKTEPDAPQPMGPNWLDCP APSSGPRAPRPPKATPVSET CDCQCELNQAA |
| Tissue Specificity | Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas. |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | May activate progelatinase A. |
| Protein Name | Matrix Metalloproteinase-25 Mmp-25 Leukolysin Membrane-Type Matrix Metalloproteinase 6 Mt-Mmp 6 Mtmmp6 Membrane-Type-6 Matrix Metalloproteinase Mt6-Mmp Mt6mmp |
| Database Links | Reactome: R-HSA-1592389 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Extracellular Side Secreted Extracellular Space Extracellular Matrix |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-25 antibody Anti-Mmp-25 antibody Anti-Leukolysin antibody Anti-Membrane-Type Matrix Metalloproteinase 6 antibody Anti-Mt-Mmp 6 antibody Anti-Mtmmp6 antibody Anti-Membrane-Type-6 Matrix Metalloproteinase antibody Anti-Mt6-Mmp antibody Anti-Mt6mmp antibody Anti-MMP25 antibody Anti-MMP20 antibody Anti-MMPL1 antibody Anti-MT6MMP antibody |
Information sourced from Uniprot.org