Anti-METTL13 antibody (540-699) (STJ29191)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal METTL13 (540-699) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | METTL13 |
| Gene ID | 51603 |
| Uniprot ID | EFNMT_HUMAN |
| Immunogen Region | 540-699 |
| Immunogen Sequence | SQSDRMKVHIADGLDYIASL AGGGEARPCYDVIMFDVDSK DPTLGMSCPPPAFVEQSFLQ KVKSILTPEGVFILNLVCRD LGLKDSVLAGLKAVFPLLYV RRIEGEVNEILFCQLHPEQK LATPELLETAQALERTLRKP GRGWDDTYVLSDMLKTVKIV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 540-699 of human METTL13 (NP_057019.3). |
Additional Info
| Function | Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. |
| Protein Name | Eef1a Lysine And N-Terminal MethyltransferaseEef1a-KnmtMethyltransferase-Like Protein 13 Includes - Eef1a Lysine Methyltransferase - Eef1a N-Terminal Methyltransferase |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusMitochondrion |
| Alternative Antibody Names | Anti-Eef1a Lysine And N-Terminal Methyltransferase antibodyAnti-Eef1a-Knmt antibodyAnti-Methyltransferase-Like Protein 13 Includes - Eef1a Lysine Methyltransferase - Eef1a N-Terminal Methyltransferase antibodyAnti-METTL13 antibodyAnti-EEF1AKNMT antibodyAnti-FEAT antibodyAnti-KIAA0859 antibodyAnti-CGI-01 antibody |
Information sourced from Uniprot.org