| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-MMP12 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlELISA-antibody detection limit dilution 1:4000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
MMP12 |
| Gene ID: |
4321 |
| Uniprot ID: |
MMP12_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_002417.2 |
| Immunogen Sequence: |
RPKTSVNLISS |
| Function | May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. |
| Protein Name | Macrophage MetalloelastaseMmeMacrophage ElastaseMeHmeMatrix Metalloproteinase-12Mmp-12 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Macrophage Metalloelastase antibodyAnti-Mme antibodyAnti-Macrophage Elastase antibodyAnti-Me antibodyAnti-Hme antibodyAnti-Matrix Metalloproteinase-12 antibodyAnti-Mmp-12 antibodyAnti-MMP12 antibodyAnti-HME antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
