Anti-MMP11 antibody (239-488) (STJ24575)

Name: Anti-MMP11 antibody (239-488) (STJ24575)
SKU: STJ24575
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ24575

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Short Description	Rabbit polyclonal MMP11 (239-488) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	MMP11
Gene ID	4320
Uniprot ID	MMP11_HUMAN
Immunogen Region	239-488
Immunogen Sequence	FRYPLSLSPDDCRGVQHLYG QPWPTVTSRTPALGPQAGID TNEIAPLEPDAPPDACEASF DAVSTIRGELFFFKAGFVWR LRGGQLQPGYPALASRHWQG LPSPVDAAFEDAQGHIWFFQ GAQYWVYDGEKPVLGPAPLT ELGLVRFPVHAALVWGPEKN KIYFFRGRDYWRFHPSTRRV DSPVPRRATDWRGVPSEIDA AFQDADGYAYFLRGRLYWKF DPVKVKALEGFPRLVGPDF
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 239-488 of human MMP11 (NP_005931.2).

Tissue Specificity	Specifically expressed in stromal cells of breast carcinomas.
Post Translational Modifications	The precursor is cleaved by a furin endopeptidase.
Function	May play an important role in the progression of epithelial malignancies.
Protein Name	Stromelysin-3 Sl-3 St3 Matrix Metalloproteinase-11 Mmp-11
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-1592389
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Stromelysin-3 antibody Anti-Sl-3 antibody Anti-St3 antibody Anti-Matrix Metalloproteinase-11 antibody Anti-Mmp-11 antibody Anti-MMP11 antibody Anti-STMY3 antibody

Information sourced from Uniprot.org