• Western blot analysis of extracts of various cell lines, using MMP11 antibody (STJ24575) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 2min.

Anti-MMP11 antibody (239-488) (STJ24575)

SKU:
STJ24575

£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MMP11
Gene ID: 4320
Uniprot ID: MMP11_HUMAN
Immunogen Region: 239-488
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 239-488 of human MMP11 (NP_005931.2).
Immunogen Sequence: FRYPLSLSPDDCRGVQHLYG QPWPTVTSRTPALGPQAGID TNEIAPLEPDAPPDACEASF DAVSTIRGELFFFKAGFVWR LRGGQLQPGYPALASRHWQG LPSPVDAAFEDAQGHIWFFQ GAQYWVYDGEKPVLGPAPLT ELGLVRFPVHAALVWGPEKN KIYFFRGRDYWRFHPSTRRV DSPVPRRATDWRGVPSEIDA AFQDADGYAYFLRGRLYWKF DPVKVKALEGFPRLVGPDF
Tissue Specificity Specifically expressed in stromal cells of breast carcinomas.
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function May play an important role in the progression of epithelial malignancies.
Protein Name Stromelysin-3
Sl-3
St3
Matrix Metalloproteinase-11
Mmp-11
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Reactome: R-HSA-1592389
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Stromelysin-3 antibody
Anti-Sl-3 antibody
Anti-St3 antibody
Anti-Matrix Metalloproteinase-11 antibody
Anti-Mmp-11 antibody
Anti-MMP11 antibody
Anti-STMY3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance