| Short Description : | Rabbit polyclonal anti-Protein AF-10 (211-260 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MLLT10 |
| Gene ID: | 8028 |
| Uniprot ID: | AF10_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human AF10 at the amino acid range 211-260 |
| Immunogen Region: | 211-260 aa |
| Specificity: | AF-10 Polyclonal Antibody detects endogenous levels of AF-10 protein. |
| Function | Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation. |
| Protein Name | Protein Af-10All1-Fused Gene From Chromosome 10 Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Af-10 antibodyAnti-All1-Fused Gene From Chromosome 10 Protein antibodyAnti-MLLT10 antibodyAnti-AF10 antibody |
Information sourced from Uniprot.org
