| Tissue Specificity | Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level). |
| Post Translational Modifications | Phosphorylated at multiple sites. |
| Function | Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression. |
| Protein Name | Homeobox Protein Mixl1Homeodomain Protein MixHmixMix1 Homeobox-Like Protein 1Mix.1 Homeobox-Like Protein |
| Database Links | Reactome: R-HSA-9754189Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Mixl1 antibodyAnti-Homeodomain Protein Mix antibodyAnti-Hmix antibodyAnti-Mix1 Homeobox-Like Protein 1 antibodyAnti-Mix.1 Homeobox-Like Protein antibodyAnti-MIXL1 antibodyAnti-MIXL antibody |
Information sourced from Uniprot.org
