| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MITD1 |
| Gene ID: | 129531 |
| Uniprot ID: | MITD1_HUMAN |
| Immunogen Region: | 1-249 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human MITD1 (NP_620153.1). |
| Immunogen Sequence: | MAKSGLRQDPQSTAAATVLK RAVELDSESRYPQALVCYQE GIDLLLQVLKGTKDNTKRCN LREKISKYMDRAENIKKYLD QEKEDGKYHKQIKIEENATG FSYESLFREYLNETVTEVWI EDPYIRHTHQLYNFLRFCEM LIKRPCKVKTIHLLTSLDEG IEQVQQSRGLQEIEESLRSH GVLLEVQYSSSIHDREIRFN NGWMIKIGRGLDYFKKPQSR FSLGYCDFDLRPCHETTVD |
| Function | Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. |
| Protein Name | Mit Domain-Containing Protein 1 |
| Cellular Localisation | Late Endosome MembranePeripheral Membrane ProteinCytoplasmic SideMidbodyMembraneDuring CytokinesisRecruited To The Midbody Via Interaction With Chmp1aInteracts With Membranes Enriched In Phosphoinositides |
| Alternative Antibody Names | Anti-Mit Domain-Containing Protein 1 antibodyAnti-MITD1 antibody |
Information sourced from Uniprot.org
