| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Melanoma inhibitory activity protein 2 (361-410 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MIA2 |
| Gene ID: |
4253 |
| Uniprot ID: |
MIA2_HUMAN |
| Immunogen Region: |
361-410 aa |
| Specificity: |
MIA2 Polyclonal Antibody detects endogenous levels of MIA2 |
| Immunogen: |
Synthesized peptide derived from MIA2 at the amino acid range 361-410 |
| Function | Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis. Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites. |
| Protein Name | Melanoma Inhibitory Activity Protein 2Mia Protein 2Ctage Family Member 5 Er Export FactorCutaneous T-Cell Lymphoma-Associated Antigen 5Meningioma-Expressed Antigen 6/11 |
| Database Links | Reactome: R-HSA-5694530 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLocalizes To Endoplasmic Reticulum Exit Sites (Eres)Also Known As Transitional Endoplasmic Reticulum (Ter) |
| Alternative Antibody Names | Anti-Melanoma Inhibitory Activity Protein 2 antibodyAnti-Mia Protein 2 antibodyAnti-Ctage Family Member 5 Er Export Factor antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen 5 antibodyAnti-Meningioma-Expressed Antigen 6/11 antibodyAnti-MIA2 antibodyAnti-CTAGE5 antibodyAnti-MEA11 antibodyAnti-MEA6 antibodyAnti-MGEA11 antibodyAnti-MGEA6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
