Anti-MFI2 antibody (20-200) (STJ28736)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MFI2 (20-200) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MELTF |
| Gene ID | 4241 |
| Uniprot ID | TRFM_HUMAN |
| Immunogen Region | 20-200 |
| Immunogen Sequence | GMEVRWCATSDPEQHKCGNM SEAFREAGIQPSLLCVRGTS ADHCVQLIAAQEADAITLDG GAIYEAGKEHGLKPVVGEVY DQEVGTSYYAVAVVRRSSHV TIDTLKGVKSCHTGINRTVG WNVPVGYLVESGRLSVMGCD VLKAVSDYFGGSCVPGAGET SYSESLCRLCRGDSSGEGVC D |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human MFI2 (NP_201573.1). |
Additional Info
| Tissue Specificity | Found predominantly in human melanomas and in certain fetal tissues.also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts. |
| Function | Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. |
| Protein Name | MelanotransferrinMelanoma-Associated Antigen P97Cd Antigen Cd228 |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Melanotransferrin antibodyAnti-Melanoma-Associated Antigen P97 antibodyAnti-Cd Antigen Cd228 antibodyAnti-MELTF antibodyAnti-MAP97 antibodyAnti-MFI2 antibody |
Information sourced from Uniprot.org