Anti-METTL7B antibody (165-244) (STJ29280)

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STJ29280
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TMT1B
Gene ID: 196410
Uniprot ID: TMT1B_HUMAN
Immunogen Region: 165-244
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 165-244 of human METTL7B (NP_689850.2).
Immunogen Sequence: RPGGVLFFWEHVAEPYGSWA FMWQQVFEPTWKHIGDGCCL TRETWKDLENAQFSEIQMER QPPPLKWLPVGPHIMGKAVK
Tissue Specificity Expressed in the liver.
Function Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to alkyl and phenolic thiol-containing acceptor substrates. Together with TMT1B accounts for most of S-thiol methylation activity in the endoplasmic reticulum of hepatocytes. Selectively methylates S-centered nucleophiles from metabolites such as hydrogen sulfide and dithiothreitol.
Protein Name Thiol S-Methyltransferase Tmt1b
Methyltransferase-Like Protein 7b
Thiol S-Methyltransferase Mettl7b
Cellular Localisation Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Lipid Droplet
Microsome
Cytoplasm
Cytosol
Highly Concentrated In The Perinuclear Area Of The Endoplasmic Reticulum (Er) And Surrounding Lipid Droplets
May Be Associated With The Specific Regions Of The Lr That Form Lipid Droplets And Targeted To The Initial Deposits Of Lipids Where The Lipid Droplets Form
Alternative Antibody Names Anti-Thiol S-Methyltransferase Tmt1b antibody
Anti-Methyltransferase-Like Protein 7b antibody
Anti-Thiol S-Methyltransferase Mettl7b antibody
Anti-TMT1B antibody
Anti-METTL7B antibody
Anti-UNQ594 antibody
Anti-PRO1180 antibody

Information sourced from Uniprot.org