Anti-MEST antibody (146-335) (STJ29011)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ29011
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General Information

Short DescriptionRabbit polyclonal MEST (146-335) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:1000-1:5000
IF/ICC:1:50-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolMEST
Gene ID4232
Uniprot IDMEST_HUMAN
Immunogen Region146-335
Immunogen SequenceHDYGDIVAQELLYRYKQNRS GRLTIKSLCLSNGGIFPETH RPLLLQKLLKDGGVLSPILT RLMNFFVFSRGLTPVFGPYT RPSESELWDMWAGIRNNDGN LVIDSLLQYINQRKKFRRRW VGALASVTIPIHFIYGPLDP VNPYPEFLELYRKTLPRSTV SILDDHISHYPQLEDPMGFL NAYMGFINSF
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 146-335 of human MEST (NP_002393.2).

Additional Info

Tissue Specificity Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele.
Protein Name Mesoderm-Specific Transcript Homolog Protein
Paternally-Expressed Gene 1 Protein
Database Links
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Mesoderm-Specific Transcript Homolog Protein antibody
Anti-Paternally-Expressed Gene 1 Protein antibody
Anti-MEST antibody
Anti-PEG1 antibody

Information sourced from Uniprot.org

Citations

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