| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MEST |
| Gene ID: | 4232 |
| Uniprot ID: | MEST_HUMAN |
| Immunogen Region: | 146-335 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 146-335 of human MEST (NP_002393.2). |
| Immunogen Sequence: | HDYGDIVAQELLYRYKQNRS GRLTIKSLCLSNGGIFPETH RPLLLQKLLKDGGVLSPILT RLMNFFVFSRGLTPVFGPYT RPSESELWDMWAGIRNNDGN LVIDSLLQYINQRKKFRRRW VGALASVTIPIHFIYGPLDP VNPYPEFLELYRKTLPRSTV SILDDHISHYPQLEDPMGFL NAYMGFINSF |
| Tissue Specificity | Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele. |
| Protein Name | Mesoderm-Specific Transcript Homolog ProteinPaternally-Expressed Gene 1 Protein |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mesoderm-Specific Transcript Homolog Protein antibodyAnti-Paternally-Expressed Gene 1 Protein antibodyAnti-MEST antibodyAnti-PEG1 antibody |
Information sourced from Uniprot.org