Anti-MEMO1 antibody (1-297aa) [AT1E9] (STJA0041630)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human MEMO1 (1-297aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-MEMO1 (1-297aa) for use in ELISA, WB and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/FACS |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1E9 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MEMO1 |
| Gene ID | 51072 |
| Uniprot ID | MEMO1_HUMAN |
| Accession Number | NP_057039 |
| Immunogen | Recombinant human MEMO1 (1-297aa) purified from E. coli |
| Immunogen Region | 1-297aa |
Additional Info
| Function | May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. |
| Protein Name | Protein Memo1C21orf19-Like ProteinHepatitis C Virus Ns5a-Transactivated Protein 7Hcv Ns5a-Transactivated Protein 7Mediator Of Erbb2-Driven Cell Motility 1Mediator Of Cell Motility 1Memo-1 |
| Database Links | Reactome: R-HSA-6785631 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Protein Memo1 antibodyAnti-C21orf19-Like Protein antibodyAnti-Hepatitis C Virus Ns5a-Transactivated Protein 7 antibodyAnti-Hcv Ns5a-Transactivated Protein 7 antibodyAnti-Mediator Of Erbb2-Driven Cell Motility 1 antibodyAnti-Mediator Of Cell Motility 1 antibodyAnti-Memo-1 antibodyAnti-MEMO1 antibodyAnti-C2orf4 antibodyAnti-MEMO antibodyAnti-NS5ATP7 antibodyAnti-CGI-27 antibody |
Information sourced from Uniprot.org