Anti-MED6 antibody (27-246) (STJ110480)

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STJ110480
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MED6
Gene ID: 10001
Uniprot ID: MED6_HUMAN
Immunogen Region: 27-246
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 27-246 of human MED6 (NP_005457.2).
Immunogen Sequence: GSVLDYFSERSNPFYDRTCN NEVVKMQRLTLEHLNQMVGI EYILLHAQEPILFIIRKQQR QSPAQVIPLADYYIIAGVIY QAPDLGSVINSRVLTAVHGI QSAFDEAMSYCRYHPSKGYW WHFKDHEEQDKVRPKAKRKE EPSSIFQRQRVDALLLDLRQ KFPPKFVQLKPGEKPVPVDQ TKKEAEPIPETVKPEEKETT KNVQQTVSAKGPPEKRMRLQ
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Protein Name Mediator Of Rna Polymerase Ii Transcription Subunit 6
Activator-Recruited Cofactor 33 Kda Component
Arc33
Mediator Complex Subunit 6
Hmed6
Renal Carcinoma Antigen Ny-Ren-28
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-212436
Reactome: R-HSA-381340
Reactome: R-HSA-9833110
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 6 antibody
Anti-Activator-Recruited Cofactor 33 Kda Component antibody
Anti-Arc33 antibody
Anti-Mediator Complex Subunit 6 antibody
Anti-Hmed6 antibody
Anti-Renal Carcinoma Antigen Ny-Ren-28 antibody
Anti-MED6 antibody
Anti-ARC33 antibody

Information sourced from Uniprot.org