Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 6Activator-Recruited Cofactor 33 Kda ComponentArc33Mediator Complex Subunit 6Hmed6Renal Carcinoma Antigen Ny-Ren-28 |
Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 6 antibodyAnti-Activator-Recruited Cofactor 33 Kda Component antibodyAnti-Arc33 antibodyAnti-Mediator Complex Subunit 6 antibodyAnti-Hmed6 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-28 antibodyAnti-MED6 antibodyAnti-ARC33 antibody |
Information sourced from Uniprot.org