| Tissue Specificity | Ubiquitous. |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 14Activator-Recruited Cofactor 150 Kda ComponentArc150Cofactor Required For Sp1 Transcriptional Activation Subunit 2Crsp Complex Subunit 2Mediator Complex Subunit 14Rgr1 HomologHrgr1Thyroid Hormone Receptor-Associated Protein Complex 170 Kda ComponentTrap170Transcriptional Coactivator Crsp150Vitamin D3 Receptor-Interacting Protein Complex 150 Kda ComponentDrip150 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 14 antibodyAnti-Activator-Recruited Cofactor 150 Kda Component antibodyAnti-Arc150 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 2 antibodyAnti-Crsp Complex Subunit 2 antibodyAnti-Mediator Complex Subunit 14 antibodyAnti-Rgr1 Homolog antibodyAnti-Hrgr1 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 170 Kda Component antibodyAnti-Trap170 antibodyAnti-Transcriptional Coactivator Crsp150 antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex 150 Kda Component antibodyAnti-Drip150 antibodyAnti-MED14 antibodyAnti-ARC150 antibodyAnti-CRSP2 antibodyAnti-CXorf4 antibodyAnti-DRIP150 antibodyAnti-EXLM1 antibodyAnti-RGR1 antibodyAnti-TRAP170 antibody |
Information sourced from Uniprot.org
