| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 13-LikeMediator Complex Subunit 13-LikeThyroid Hormone Receptor-Associated Protein 2Thyroid Hormone Receptor-Associated Protein Complex 240 Kda Component-Like |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 13-Like antibodyAnti-Mediator Complex Subunit 13-Like antibodyAnti-Thyroid Hormone Receptor-Associated Protein 2 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 240 Kda Component-Like antibodyAnti-MED13L antibodyAnti-KIAA1025 antibodyAnti-PROSIT240 antibodyAnti-THRAP2 antibodyAnti-TRAP240L antibody |
Information sourced from Uniprot.org
