| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Enoyl-acyl-carrier-protein reductase, mitochondrial (160-210 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MECR |
| Gene ID: |
51102 |
| Uniprot ID: |
MECR_HUMAN |
| Immunogen Region: |
160-210 aa |
| Specificity: |
This antibody detects endogenous levels of MECR at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human MECR at the amino acid range 160-210 |
| Function | Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells. |
| Protein Name | Enoyl-Acyl-Carrier-Protein Reductase - Mitochondrial2-Enoyl Thioester ReductaseNuclear Receptor-Binding Factor 1Hsnrbf-1Nrbf-1 |
| Database Links | Reactome: R-HSA-77346 |
| Cellular Localisation | Isoform 1: MitochondrionIsoform 2: CytoplasmNucleus |
| Alternative Antibody Names | Anti-Enoyl-Acyl-Carrier-Protein Reductase - Mitochondrial antibodyAnti-2-Enoyl Thioester Reductase antibodyAnti-Nuclear Receptor-Binding Factor 1 antibodyAnti-Hsnrbf-1 antibodyAnti-Nrbf-1 antibodyAnti-MECR antibodyAnti-NBRF1 antibodyAnti-CGI-63 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
