Anti-MEAF6 antibody (1-191) (STJ116836)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MEAF6 (1-191) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MEAF6 |
| Gene ID | 64769 |
| Uniprot ID | EAF6_HUMAN |
| Immunogen Region | 1-191 |
| Immunogen Sequence | MAMHNKAAPPQIPDTRRELA ELVKRKQELAETLANLERQI YAFEGSYLEDTQMYGNIIRG WDRYLTNQKNSNSKNDRRNR KFKEAERLFSKSSVTSAAAV SALAGVQDQLIEKREPGSGT ESDTSPDFHNQENEPSQEDP EDLDGSVQGVKPQKAASSTS SGSHHSSHKKRKNKNRHRID LKLNKKPRADY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human MEAF6 (NP_001257804.1). |
Additional Info
| Function | Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. |
| Protein Name | Chromatin Modification-Related Protein Meaf6Myst/Esa1-Associated Factor 6Esa1-Associated Factor 6 HomologProtein Eaf6 HomologHeaf6Sarcoma Antigen Ny-Sar-91 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-6804758 |
| Cellular Localisation | NucleusNucleolusChromosomeCentromereKinetochore |
| Alternative Antibody Names | Anti-Chromatin Modification-Related Protein Meaf6 antibodyAnti-Myst/Esa1-Associated Factor 6 antibodyAnti-Esa1-Associated Factor 6 Homolog antibodyAnti-Protein Eaf6 Homolog antibodyAnti-Heaf6 antibodyAnti-Sarcoma Antigen Ny-Sar-91 antibodyAnti-MEAF6 antibodyAnti-C1orf149 antibodyAnti-CENP-28 antibodyAnti-EAF6 antibody |
Information sourced from Uniprot.org