• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-MCRIP1 antibody (14-64 aa) (STJ196193)

SKU:
STJ196193

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mapk-regulated corepressor-interacting protein 1 (14-64 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MCRIP1
Gene ID: 348262
Uniprot ID: MCRI1_HUMAN
Immunogen Region: 14-64 aa
Specificity: This antibody detects endogenous levels of F195B at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human F195B at the amino acid range 14-64
Function The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition.
Protein Name Mapk-Regulated Corepressor-Interacting Protein 1
Granulin-2
Protein Fam195b
Cellular Localisation Nucleus
Cytoplasm
Stress Granule
Alternative Antibody Names Anti-Mapk-Regulated Corepressor-Interacting Protein 1 antibody
Anti-Granulin-2 antibody
Anti-Protein Fam195b antibody
Anti-MCRIP1 antibody
Anti-FAM195B antibody
Anti-GRAN2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance