| Short Description : | Rabbit polyclonal MCCC2 (284-563) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MCCC2 |
| Gene ID: | 64087 |
| Uniprot ID: | MCCB_HUMAN |
| Immunogen Region: | 284-563 |
| Immunogen Sequence: | LHLTRKVVRNLNYQKKLDVT IEPSEEPLFPADELYGIVGA NLKRSFDVREVIARIVDGSR FTEFKAFYGDTLVTGFARIF GYPVGIVGNNGVLFSESAKK GTHFVQLCCQRNIPLLFLQN ITGFMVGREYEAEGIAKDGA KMVAAVACAQVPKITLIIGG SYGAGNYGMCGRAYSPRFLY IWPNARISVMGGEQAANVLA TITKDQRAREGKQFSSADEA ALKEPIIKKFEEEGNPYYS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human MCCC2 (NP_071415.1). |
| Function | Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. |
| Protein Name | Methylcrotonoyl-Coa Carboxylase Beta Chain - MitochondrialMccase Subunit Beta3-Methylcrotonyl-Coa Carboxylase 23-Methylcrotonyl-Coa Carboxylase Non-Biotin-Containing Subunit3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Beta |
| Database Links | Reactome: R-HSA-196780Reactome: R-HSA-3371599Reactome: R-HSA-70895Reactome: R-HSA-9909438 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Methylcrotonoyl-Coa Carboxylase Beta Chain - Mitochondrial antibodyAnti-Mccase Subunit Beta antibodyAnti-3-Methylcrotonyl-Coa Carboxylase 2 antibodyAnti-3-Methylcrotonyl-Coa Carboxylase Non-Biotin-Containing Subunit antibodyAnti-3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Beta antibodyAnti-MCCC2 antibodyAnti-MCCB antibody |
Information sourced from Uniprot.org
