Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Melanocyte-stimulating hormone receptor (268-317 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MC1R |
Gene ID: |
4157 |
Uniprot ID: |
MSHR_HUMAN |
Immunogen Region: |
268-317 aa |
Specificity: |
MC1-R Polyclonal Antibody detects endogenous levels of MC1-R protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human MSHR at the amino acid range 268-317 |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes. |
Protein Name | Melanocyte-Stimulating Hormone ReceptorMsh-RMelanocortin Receptor 1Mc1-R |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Melanocyte-Stimulating Hormone Receptor antibodyAnti-Msh-R antibodyAnti-Melanocortin Receptor 1 antibodyAnti-Mc1-R antibodyAnti-MC1R antibodyAnti-MSHR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance