Anti-MBL antibody [3+00E+07] (STJ16100773)

SKU:
STJ16100773-1

£843.50
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Host: Mouse
Applications: IHC-F/FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-MBL is suitable for use in Immunohistochemistry, Flow Cytometry and ELISA research applications.
Clonality: Monoclonal
Clone ID: 3+00E+07
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Concentration: 100 ug/mL
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: MBL2
Gene ID: 4153
Uniprot ID: MBL2_HUMAN
Tissue Specificity Plasma protein produced mainly in the liver.
Function Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. Upon SARS coronavirus-2/SARS-CoV-2 infection, activates the complement lectin pathway which leads to the inhibition SARS-CoV-2 infection and a reduction of the induced inflammatory response.
Protein Name Mannose-Binding Protein C
Mbp-C
Collectin-1
Mbp1
Mannan-Binding Protein
Mannose-Binding Lectin
Database Links Reactome: R-HSA-166662
Reactome: R-HSA-166663
Reactome: R-HSA-9705671
Cellular Localisation Secreted
Alternative Antibody Names Anti-Mannose-Binding Protein C antibody
Anti-Mbp-C antibody
Anti-Collectin-1 antibody
Anti-Mbp1 antibody
Anti-Mannan-Binding Protein antibody
Anti-Mannose-Binding Lectin antibody
Anti-MBL2 antibody
Anti-COLEC1 antibody
Anti-MBL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance