Anti-MB antibody (1-154) (STJ27424)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MB (1-154) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MB |
| Gene ID | 4151 |
| Uniprot ID | MYG_HUMAN |
| Immunogen Region | 1-154 |
| Immunogen Sequence | MGLSDGEWQLVLNVWGKVEA DIPGHGQEVLIRLFKGHPET LEKFDKFKHLKSEDEMKASE DLKKHGATVLTALGGILKKK GHHEAEIKPLAQSHATKHKI PVKYLEFISECIIQVLQSKH PGDFGADAQGAMNKALELFR KDMASNYKELGFQG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human Myoglobin (NP_005359.1). |
Additional Info
| Function | Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity. |
| Protein Name | MyoglobinNitrite Reductase MbPseudoperoxidase Mb |
| Database Links | Reactome: R-HSA-8981607 |
| Cellular Localisation | CytoplasmSarcoplasm |
| Alternative Antibody Names | Anti-Myoglobin antibodyAnti-Nitrite Reductase Mb antibodyAnti-Pseudoperoxidase Mb antibodyAnti-MB antibody |
Information sourced from Uniprot.org