Anti-MATK antibody [9D7] (STJ98225)

SKU:
STJ98225
£149.00 - £360.00
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Short Description :Mouse monoclonal anti-Megakaryocyte-associated tyrosine-protein kinase for use in WB, FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/FC/ELISA
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :9D7
Isotype:IgG1
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Antibody are purified by protein G affinity chromatography.
Dilution Range:WB 1:500-1:2000
FC 1:200-1:400
ELISA 1:10000
Formulation:Liquid in PBS containing 50% Glycerol and 0.03% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MATK
Gene ID:4145
Uniprot ID:MATK_HUMAN
Immunogen:Purified recombinant fragment of human Lsk expressed in E. Coli.
Specificity:Lsk Monoclonal Antibody detects endogenous levels of Lsk protein.
Function Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Protein Name Megakaryocyte-Associated Tyrosine-Protein Kinase
Csk Homologous Kinase
Chk
Hematopoietic Consensus Tyrosine-Lacking Kinase
Protein Kinase Hyl
Tyrosine-Protein Kinase Ctk
Database Links Reactome: R-HSA-8863795
Cellular Localisation Cytoplasm
Membrane
In Platelets
90% Of Matk Localizes To The Membrane Fraction
And Translocates To The Cytoskeleton Upon Thrombin Stimulation
Alternative Antibody Names Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibody
Anti-Csk Homologous Kinase antibody
Anti-Chk antibody
Anti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibody
Anti-Protein Kinase Hyl antibody
Anti-Tyrosine-Protein Kinase Ctk antibody
Anti-MATK antibody
Anti-CTK antibody
Anti-HYL antibody

Information sourced from Uniprot.org