Anti-MATK antibody [9D7] (STJ98225)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of human Lsk expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Megakaryocyte-associated tyrosine-protein kinase for use in WB, FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 9D7 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Antibody are purified by protein G affinity chromatography. |
| Dilution Range | WB 1:500-1:2000FC 1:200-1:400ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.03% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MATK |
| Gene ID | 4145 |
| Uniprot ID | MATK_HUMAN |
| Immunogen | Purified recombinant fragment of human Lsk expressed in E. Coli. |
| Specificity | Lsk Monoclonal Antibody detects endogenous levels of Lsk protein. |
Additional Info
| Function | Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. |
| Protein Name | Megakaryocyte-Associated Tyrosine-Protein KinaseCsk Homologous KinaseChkHematopoietic Consensus Tyrosine-Lacking KinaseProtein Kinase HylTyrosine-Protein Kinase Ctk |
| Database Links | Reactome: R-HSA-8863795 |
| Cellular Localisation | CytoplasmMembraneIn Platelets90% Of Matk Localizes To The Membrane FractionAnd Translocates To The Cytoskeleton Upon Thrombin Stimulation |
| Alternative Antibody Names | Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibodyAnti-Csk Homologous Kinase antibodyAnti-Chk antibodyAnti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibodyAnti-Protein Kinase Hyl antibodyAnti-Tyrosine-Protein Kinase Ctk antibodyAnti-MATK antibodyAnti-CTK antibodyAnti-HYL antibody |
Information sourced from Uniprot.org