| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MARS1 |
| Gene ID: | 4141 |
| Uniprot ID: | SYMC_HUMAN |
| Immunogen Region: | 1-270 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MARS (NP_004981.2). |
| Immunogen Sequence: | MRLFVSDGVPGCLPVLAAAG RARGRAEVLISTVGPEDCVV PFLTRPKVPVLQLDSGNYLF STSAICRYFFLLSGWEQDDL TNQWLEWEATELQPALSAAL YYLVVQGKKGEDVLGSVRRA LTHIDHSLSRQNCPFLAGET ESLADIVLWGALYPLLQDPA YLPEELSALHSWFQTLSTQE PCQRAAETVLKQQGVLALRP YLQKQPQPSPAEGRAVTNEP EEEELATLSEEEIAMAVTA |
| Function | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus. |
| Protein Name | Methionine--Trna Ligase - CytoplasmicMethionyl-Trna SynthetaseMetrs |
| Database Links | Reactome: R-HSA-2408522Reactome: R-HSA-379716Reactome: R-HSA-9856649 |
| Cellular Localisation | CytoplasmCytosolNucleusNucleolusLocalizes To The Nucleolus In Proliferative Cells But Disappears In Quiescent Cells |
| Alternative Antibody Names | Anti-Methionine--Trna Ligase - Cytoplasmic antibodyAnti-Methionyl-Trna Synthetase antibodyAnti-Metrs antibodyAnti-MARS1 antibodyAnti-MARS antibody |
Information sourced from Uniprot.org