| Host: |
Chicken |
| Applications: |
WB/IHC/ICC |
| Reactivity: |
Human/Non-Human Primates |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Chicken polyclonal antibody anti-MARCKS is suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgY |
| Formulation: |
Total IgY fraction in PBS + 10 mM Sodium Azide. |
| Purification: |
This antibody was total igy fraction. |
| Dilution Range: |
WB 1:10000IHC 1:500-1:1000ICC 1:500-1:5000IP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MARCKS |
| Gene ID: |
4082 |
| Uniprot ID: |
MARCS_HUMAN |
| Immunogen: |
Recombinant human MARCKS expressed in and purified from E. coli |
| Post Translational Modifications | Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity. |
| Function | MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. |
| Protein Name | Myristoylated Alanine-Rich C-Kinase SubstrateMarcksProtein Kinase C Substrate - 80 Kda Protein - Light Chain80k-L ProteinPkcsl |
| Database Links | Reactome: R-HSA-399997 |
| Cellular Localisation | CytoplasmCytoskeletonMembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Myristoylated Alanine-Rich C-Kinase Substrate antibodyAnti-Marcks antibodyAnti-Protein Kinase C Substrate - 80 Kda Protein - Light Chain antibodyAnti-80k-L Protein antibodyAnti-Pkcsl antibodyAnti-MARCKS antibodyAnti-MACS antibodyAnti-PRKCSL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
