Anti-MARCH9 antibody (277-346) (STJ112609)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MARCH9 (277-346) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MARCHF9 |
| Gene ID | 92979 |
| Uniprot ID | MARH9_HUMAN |
| Immunogen Region | 277-346 |
| Immunogen Sequence | GTAGKSGPRNSRTGPTSGAT SRPPAAQRMRTLLPQRCGYT ILHLLGQLRPPDARSSSHSG REVVMRVTTV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 277-346 of human MARCH9 (NP_612405.2). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| Protein Name | E3 Ubiquitin-Protein Ligase Marchf9Membrane-Associated Ring Finger Protein 9Membrane-Associated Ring-Ch Protein IxMarch-IxRing Finger Protein 179Ring-Type E3 Ubiquitin Transferase Marchf9 |
| Database Links | |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinLysosome Membrane |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Marchf9 antibodyAnti-Membrane-Associated Ring Finger Protein 9 antibodyAnti-Membrane-Associated Ring-Ch Protein Ix antibodyAnti-March-Ix antibodyAnti-Ring Finger Protein 179 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Marchf9 antibodyAnti-MARCHF9 antibodyAnti-MARCH9 antibodyAnti-RNF179 antibody |
Information sourced from Uniprot.org