| Host: | Rat |
| Applications: | WB/ICC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rat monoclonal antibody anti-EB2 is suitable for use in Western Blot and Immunocytochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | KT52 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Formulation: | PBS + 0.05% NaN3 |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:1000ICC 1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAPRE2 |
| Gene ID: | 10982 |
| Uniprot ID: | MARE2_HUMAN |
| Specificity: | The antibody detects a 36 kDa* protein corresponding to the molecular mass of EB2 on SDS-PAGE immunoblots of human HeLa, mouse brain, and rat PC12 cells. The antibody also detects EB2 by immunocytochemistry in HeLa and A431 cells. |
| Immunogen: | Clone KT52 was generated from a GST fusion protein containing human EB2. This sequence is highly conserved in rat and mouse EB2. |
| Tissue Specificity | Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes. |
| Function | May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. |
| Protein Name | Microtubule-Associated Protein Rp/Eb Family Member 2Apc-Binding Protein Eb2End-Binding Protein 2Eb2 |
| Cellular Localisation | CytoplasmCytoskeletonAssociated With The Microtubule NetworkAccumulates At The Plus End Of Microtubules |
| Alternative Antibody Names | Anti-Microtubule-Associated Protein Rp/Eb Family Member 2 antibodyAnti-Apc-Binding Protein Eb2 antibodyAnti-End-Binding Protein 2 antibodyAnti-Eb2 antibodyAnti-MAPRE2 antibodyAnti-RP1 antibody |
Information sourced from Uniprot.org