| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-C-Jun-amino-terminal kinase-interacting protein 2 (581-630 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAPK8IP2 |
| Gene ID: | 23542 |
| Uniprot ID: | JIP2_HUMAN |
| Immunogen Region: | 581-630 aa |
| Specificity: | JIP-2 Polyclonal Antibody detects endogenous levels of JIP-2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human JIP2 at the amino acid range 581-630 |
| Function | The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. |
| Protein Name | C-Jun-Amino-Terminal Kinase-Interacting Protein 2Jip-2Jnk-Interacting Protein 2Islet-Brain-2Ib-2Jnk Map Kinase Scaffold Protein 2Mitogen-Activated Protein Kinase 8-Interacting Protein 2 |
| Cellular Localisation | CytoplasmAccumulates In Cell Surface Projections |
| Alternative Antibody Names | Anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 2 antibodyAnti-Jip-2 antibodyAnti-Jnk-Interacting Protein 2 antibodyAnti-Islet-Brain-2 antibodyAnti-Ib-2 antibodyAnti-Jnk Map Kinase Scaffold Protein 2 antibodyAnti-Mitogen-Activated Protein Kinase 8-Interacting Protein 2 antibodyAnti-MAPK8IP2 antibodyAnti-IB2 antibodyAnti-JIP2 antibodyAnti-PRKM8IPL antibody |
Information sourced from Uniprot.org