| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Mitogen-activated protein kinase kinase kinase 21 (631-680) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAP3K21 |
| Gene ID: | 84451 |
| Uniprot ID: | M3K21_HUMAN |
| Immunogen Region: | 631-680 |
| Specificity: | MLK4 Polyclonal Antibody detects endogenous levels of MLK4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680 |
| Post Translational Modifications | Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. |
| Function | Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 21Mitogen-Activated Protein Kinase Kinase Kinase Mlk4Mixed Lineage Kinase 4 |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 21 antibodyAnti-Mitogen-Activated Protein Kinase Kinase Kinase Mlk4 antibodyAnti-Mixed Lineage Kinase 4 antibodyAnti-MAP3K21 antibodyAnti-KIAA1804 antibodyAnti-MLK4 antibody |
Information sourced from Uniprot.org