Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Mitogen-activated protein kinase kinase kinase 21 (631-680) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MAP3K21 |
Gene ID: |
84451 |
Uniprot ID: |
M3K21_HUMAN |
Immunogen Region: |
631-680 |
Specificity: |
MLK4 Polyclonal Antibody detects endogenous levels of MLK4 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680 |
Post Translational Modifications | Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. |
Function | Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways. |
Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 21Mitogen-Activated Protein Kinase Kinase Kinase Mlk4Mixed Lineage Kinase 4 |
Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 21 antibodyAnti-Mitogen-Activated Protein Kinase Kinase Kinase Mlk4 antibodyAnti-Mixed Lineage Kinase 4 antibodyAnti-MAP3K21 antibodyAnti-KIAA1804 antibodyAnti-MLK4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance