• Western blot of rat cortical lysate showing specific immunolabeling of the ~280 kDa MAP2 protein.
  • Immunofluorescence of a section of rat brain stem showing specific labeling of MAP2 (cat. STJA0003848, 1:2000, red) in the perikarya and dendrites of neurons and specific labeling of the myelin sheath around axons with anti-MBP ( cat. STJA0003695, 1:5000, green). The blue is DAPI revealing nuclear DNA.
  • Immunofluorescent image of primary mouse neurons specifically labelling MAP2 (STJA0003848, 1:1000, red). The blue nuclear stain is Hoechst. The image was kindly provided by Noah Johnson, University of Colorado, Anschutz Medical Campus.

Anti-MAP2-MAP2 antibody (STJA0003848)

SKU:
STJA0003848-100

£442.50
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Host: Goat
Applications: WB/IHC/ICC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Microtubule Associated Protein 2-MAP2 is suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 ul in PBS + 50% Glycerol and 5 mm Sodium Azide
Purification: This antibody was protein g purified from serum.
Dilution Range: WB 1:1000
IHC 1:1000-1:2000
ICC 1:1000-1:2000
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAP2
Gene ID: 4133
Uniprot ID: MTAP2_HUMAN
Immunogen: recombinant human MAP2 protein expressed in and purified from E. Coli
Post Translational Modifications Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67. The interaction with KNDC1 enhances MAP2 threonine phosphorylation.
Function The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Protein Name Microtubule-Associated Protein 2
Map-2
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Dendrite
Alternative Antibody Names Anti-Microtubule-Associated Protein 2 antibody
Anti-Map-2 antibody
Anti-MAP2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance