| Host: |
Mouse |
| Applications: |
WB/IHC/ICC |
| Reactivity: |
Bovine/Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Microtubule Associated Protein 2-MAP2 is suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
4H5 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
100 ul in PBS + 50% Glycerol and 5 mM Sodium Azide |
| Purification: |
This antibody was protein g purified culture from supernatant. |
| Dilution Range: |
WB 1:1000IHC 1:1000ICC 1:1000IP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Post Translational Modifications | Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67. The interaction with KNDC1 enhances MAP2 threonine phosphorylation. |
| Function | The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. |
| Protein Name | Microtubule-Associated Protein 2Map-2 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionDendrite |
| Alternative Antibody Names | Anti-Microtubule-Associated Protein 2 antibodyAnti-Map-2 antibodyAnti-MAP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
