| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAN1A2 |
| Gene ID: | 10905 |
| Uniprot ID: | MA1A2_HUMAN |
| Immunogen Region: | 60-180 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human MAN1A2 (NP_006690.1). |
| Immunogen Sequence: | SSKHKRFDLGLEDVLIPHVD AGKGAKNPGVFLIHGPDEHR HREEEERLRNKIRADHEKAL EEAKEKLRKSREEIRAEIQT EKNKVVQEMKIKENKPLPPV PIPNLVGIRGGDPEDNDIRE K |
| Tissue Specificity | Highest levels of expression in placenta and testis. |
| Function | Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). |
| Protein Name | Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase IbMannosidase Alpha Class 1a Member 2Processing Alpha-1 -2-Mannosidase IbAlpha-1 -2-Mannosidase Ib |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-964827 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase Ib antibodyAnti-Mannosidase Alpha Class 1a Member 2 antibodyAnti-Processing Alpha-1 -2-Mannosidase Ib antibodyAnti-Alpha-1 -2-Mannosidase Ib antibodyAnti-MAN1A2 antibodyAnti-MAN1B antibody |
Information sourced from Uniprot.org